Melanotan-I

Chemistry

Field	Value
Compound class	Tridecapeptide (13 aa, α-MSH analog)
Identity	Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂
Formula	C₇₈H₁₁₁N₂₁O₁₉
Molecular weight	1646.87
CAS	75921-69-6
PubChem	PubChem CID 16154396 (opens in a new tab)

Structure

PubChem properties

Property	Value
IUPAC name	(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-5-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Molecular weight	1646.8
Exact mass	1645.83651040
XLogP	-3.5
TPSA	643
InChIKey	UAHFGYDRQSXQEB-LEBBXHLNSA-N
SMILES	CCCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N5CCC[C@H]5C(=O)N[C@@H](C(C)C)C(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC6=CC=C(C=C6)O)NC(=O)[C@H](CO)NC(=O)C

Synonyms

(Nle4,D-Phe7)-alpha-MSH, [Nle4,D-Phe7]-alpha-MSH, scenesse, Melanotan-I, Afamelanotide [INN], UNII-QW68W3J66U, MBJ 05, AFAMELANOTIDE [MI], Afamelanotide [USAN:INN], AFAMELANOTIDE [USAN], [Nle4,D-Phe7]--MSH, orb321113, (nle4,d-phe7)-.alpha.-msh, AFAMELANOTIDE [WHO-DD], SCHEMBL22463810, SCHEMBL22463811, AFAMELANOTIDE [ORANGE BOOK], [Nle(4),D-Phe(7)]-alpha-MSH, EBC-27577, DA-48757, (Nle4,D-Phe7)-alpha-MSH trifluoroacetate salt, Afamelanotide; MT-I; [Nle4,D-Phe7]-alpha-MSH, EN300-18527915, alpha-Melanotropin, 4-L-norleucine-7-D-phenylalanine-, .ALPHA.-MELANOTROPIN (SWINE), 4-L-NORLEUCINE-7-D-PHENYLALANINE-

Products containing this compound

Product	Milligrams
Melanotan-I	entire fill